https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 An examination of the neutralization of in vitro toxicity of Chinese cobra (Naja atra) venom by different antivenoms https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38528 Wed 27 Oct 2021 16:09:11 AEDT ]]> Isolation and pharmacological characterization of α-Elapitoxin-Na1a, a novel short-chain postsynaptic neurotoxin from the venom of the Chinese Cobra (Naja atra) https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44896 98% amino acid sequence similarity with short-chain postsynaptic neurotoxins from other Naja species. When compared to short-chain neurotoxins isolated from cobras in China, α-EPTX-Na1a contained novel residues K47Q (i.e. lysine to glutamine), N48T (i.e. asparagine to threonine) and G49A (i.e. glycine to alanine). In conclusion, α-EPTX-Na1a is a potent, pseudo-irreversible, short-chain neurotoxin. The high prevalence of α-EPTX-Na1a in Chinese N. atra venom is likely to explain the mild neurotoxicity experienced by envenomed patients.]]> Tue 28 Nov 2023 12:09:36 AEDT ]]>